• Effect of early bosentan administration on the development of esophageal varices in cirrhotic rats: experimental study in Wistar rats 

      Rafailidis, S.; Ballas, K.; Psarras, K.; Pavlidis, T.; Emoniotou, E.; Papamichali, R.; Kalodimos, G.; Marakis, G.; Sakadamis, A.; Koukoulis, G. (2008)
      This study was conducted to investigate the effect of chronic bosentan administration on the development of esophageal varices in carbon tetrachloride-induced cirrhosis in rats. For the development of liver cirrhosis and ...
    • Hepatocyte autotaxin expression promotes liver fibrosis and cancer 

      Kaffe E., Katsifa A., Xylourgidis N., Ninou I., Zannikou M., Harokopos V., Foka P., Dimitriadis A., Evangelou K., Moulas A.N., Georgopoulou U., Gorgoulis V.G., Dalekos G.N., Aidinis V. (2017)
      Autotaxin (ATX) is a secreted lysophospholipase D that catalyzes the production of lysophosphatidic acid (LPA), a pleiotropic growth-factor–like lysophospholipid. Increased ATX expression has been detected in various chronic ...
    • Mechanisms involved in oxidative stress regulation 

      Kouretas, D.; Tsatsakis, A. M.; Domingo, J. L.; Wallace Hayes, A. (2013)
    • Oval cell proliferation in cirrhosis in rats. An experimental study 

      Tsamandas, A. C.; Antonacopoulou, A.; Kalogeropoulou, C.; Tsota, I.; Zabakis, P.; Giannopoulou, E.; Liava, A.; Tzelepi, V.; Tepetes, K.; Petsas, T.; Kardamakis, D.; Kalofonos, H. P. (2007)
      Oval cells are liver stem cells involved in liver regeneration following liver damage. Previous studies have shown that pretreatment with a hepatocyte inhibitor is required to allow full oval cell activation. This study ...